Policy issues in interconnecting networks

To support the activities of the Federal Research Coordinating Committee (FRICC) in creating an interconnected set of networks to serve the research community, two workshops were held to address the technical support of policy issues that arise when interconnecting such networks. The workshops addressed the required and feasible technologies and architectures that could be used to satisfy the desired policies for interconnection. The results of the workshop are documented

Telescience testbed pilot program

The Universities Space Research Association (USRA), under sponsorship from the NASA Office of Space Science and Applications, is conducting a Telescience Testbed Pilot Program. Fifteen universities, under subcontract to USRA, are conducting a variety of scientific experiments using advanced technology to determine the requirements and evaluate the tradeoffs for the information system of the Space Station era. An interim set of recommendations based on the experiences of the first six months of the pilot program is presented

Telescience Testbed Pilot Program

The Telescience Testbed Pilot Program is developing initial recommendations for requirements and design approaches for the information systems of the Space Station era. During this quarter, drafting of the final reports of the various participants was initiated. Several drafts are included in this report as the University technical reports

Telescience testbedding: An implementation approach

Telescience is the term used to describe a concept being developed by NASA's Office of Space Science and Applications (OSSA) under the Science and Applications Information System (SAIS) Program. This concept focuses on the development of an ability for all OSSA users to be remotely interactive with all provided information system services for the Space Station era. This concept includes access to services provided by both flight and ground components of the system and emphasizes the accommodation of users from their home institutions. Key to the development of the telescience capability is an implementation approach called rapid-prototype testbedding. This testbedding is used to validate the concept and test the applicability of emerging technologies and operational methodologies. Testbedding will be used to first determine the feasibility of an idea and then the applicability to real science usage. Once a concept is deemed viable, it will be integrated into the operational system for real time support. It is believed that this approach will greatly decrease the expense of implementing the eventual system and will enhance the resultant capabilities of the delivered system

Telescience testbed pilot program, volume 2: Program results

Space Station Freedom and its associated labs, coupled with the availability of new computing and communications technologies, have the potential for significantly enhancing scientific research. A Telescience Testbed Pilot Program (TTPP), aimed at developing the experience base to deal with issues in the design of the future information system of the Space Station era. The testbeds represented four scientific disciplines (astronomy and astrophysics, earth sciences, life sciences, and microgravity sciences) and studied issues in payload design, operation, and data analysis. This volume, of a 3 volume set, which all contain the results of the TTPP, contains the integrated results. Background is provided of the program and highlights of the program results. The various testbed experiments and the programmatic approach is summarized. The results are summarized on a discipline by discipline basis, highlighting the lessons learned for each discipline. Then the results are integrated across each discipline, summarizing the lessons learned overall

Telescience testbed pilot program, volume 3: Experiment summaries

Space Station Freedom and its associated labs, coupled with the availability of new computing and communications technologies, have the potential for significantly enhancing scientific research. A Telescience Testbed Pilot Program (TTPP), aimed at developing the experience base to deal with issues in the design of the future information system of the Space Station era. The testbeds represented four scientific disciplines (astronomy and astrophysics, earth science, life sciences, and microgravity sciences) and studied issues in payload design, operation, and data analysis. This volume, of a 3 volume set, which all contain the results of the TTPP, presents summaries of the experiments. This experiment involves the evaluation of the current Internet for the use of file and image transfer between SIRTF instrument teams. The main issue addressed was current network response times

Computer networks for remote laboratories in physics and engineering

This paper addresses a relatively new approach to scientific research, telescience, which is the conduct of scientific operations in locations remote from the site of central experimental activity. A testbed based on the concepts of telescience is being developed to ultimately enable scientific researchers on earth to conduct experiments onboard the Space Station. This system along with background materials are discussed

Collaboration technology and space science

A summary of available collaboration technologies and their applications to space science is presented as well as investigations into remote coaching paradigms and the role of a specific collaboration tool for distributed task coordination in supporting such teleoperations. The applicability and effectiveness of different communication media and tools in supporting remote coaching are investigated. One investigation concerns a distributed check-list, a computer-based tool that allows a group of people, e.g., onboard crew, ground based investigator, and mission control, to synchronize their actions while providing full flexibility for the flight crew to set the pace and remain on their operational schedule. This autonomy is shown to contribute to morale and productivity

Securing future decentralised industrial IoT infrastructures: challenges and free open source solutions

peer-reviewedThe next industrial revolution is said to be paved by the use of novel Internet of Things (IoT) technology. One important aspect of the modern IoT infrastructures is decentralised communication, often called Peer-to-Peer (P2P). In the context of industrial communication, P2P contributes to resilience and improved stability for industrial components. Current industrial facilities, however, still rely on centralised networking schemes which are considered to be mandatory to comply with security standards. In order to succeed, introduced industrial P2P technology must maintain the current level of protection and also consider possible new threats. The presented work starts with a short analysis of well-established industrial communication infrastructures and how these could benefit from decentralised structures. Subsequently, previously undefined Information Technology (IT) security requirements are derived from the new cloud based decentralised industrial automation model architecture presented in this paper. To meet those requirements, state-of-the-art communication schemes and their open source implementations are presented and assessed for their usability in the context of industrial IoT. Finally, derived building blocks for industrial IoT P2P security are presented which are qualified to comply with the stated industrial IoT security requirements

Genomic investigations of unexplained acute hepatitis in children

Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis in children have been reported worldwide, including 278 cases in the UK1. Here we report an investigation of 38 cases, 66 age-matched immunocompetent controls and 21 immunocompromised comparator participants, using a combination of genomic, transcriptomic, proteomic and immunohistochemical methods. We detected high levels of adeno-associated virus 2 (AAV2) DNA in the liver, blood, plasma or stool from 27 of 28 cases. We found low levels of adenovirus (HAdV) and human herpesvirus 6B (HHV-6B) in 23 of 31 and 16 of 23, respectively, of the cases tested. By contrast, AAV2 was infrequently detected and at low titre in the blood or the liver from control children with HAdV, even when profoundly immunosuppressed. AAV2, HAdV and HHV-6 phylogeny excluded the emergence of novel strains in cases. Histological analyses of explanted livers showed enrichment for T cells and B lineage cells. Proteomic comparison of liver tissue from cases and healthy controls identified increased expression of HLA class 2, immunoglobulin variable regions and complement proteins. HAdV and AAV2 proteins were not detected in the livers. Instead, we identified AAV2 DNA complexes reflecting both HAdV-mediated and HHV-6B-mediated replication. We hypothesize that high levels of abnormal AAV2 replication products aided by HAdV and, in severe cases, HHV-6B may have triggered immune-mediated hepatic disease in genetically and immunologically predisposed children